4/3/2023 0 Comments Nexus spring cleaning![]() And if there is a way to screw it up I'd find it for sure. No I dont, But if it is with console commands, I have avoided using them as the fourm warns about screwing up your game bad with them. You do know how to manually remove the offending corpses? I have had about the same success rate with the scrap dead things mod. I tried Scrap everything and Spring Cleaning scraps more. seems settlement attack left overs are 50/50 on being able to scrap or not. yet it suffers from the Cell Reset Bug, and also doesn't have scrappability on all corpses. Ursprünglich geschrieben von Aries the Everdying:My personal favourite is Scrap Everything. Regarding mods, I'd like for there to be a way to scrap objects on the spot, so if I am carrying to much stuff, I'd like to be able to break things down to their base components to reduce weight. I have a different issue I'd like solved. Markfordelete completely destroys the object and it will be gone from the world forever, and not make your save file extra big (and eventually unstable and corrupt). The difference between enable/disable and markfordelete commands is that enable/disable will just make something invisible, but its still there in the save file, making it bigger and more bloated. Once something has the markfordelete tag, theres no way to remove it. There is no way to reverse this process, so thats why the enable/disable thing is there for you to double check you've got the right thing targeted. Once something has been marked for deletion, it will go poof the next time you leave the area and come back. If you are UNSURE if you have the right thing targeted, you can type "disable", hit enter, and then type "enable" and hit enter (both without quotations). You can close the console by hitting the ~ key again. Then target the corpse and type "markfordelete" without quotations and hit enter. You can remove corpses by opening the console with the ~ key. SO, I am hoping someone else has already found these things and can point me in the right direction. ![]() I hate the way getting specific Information from the web is like hand to hand combat, and never really gives you the information you want. Anyone know of a mod that does this.Īnd, Yes, I searched the nexus site and did google and you tube searches, That is how I found the 2 mods I got so far, but, the searches either turn up a list of only a few items or they give me so much to go though that it seems like it would take a lifetime to see if any of it is relevent. If it's dead and within my settlement boundries I want it gone and I want the resorces it contains. Anyone know of a mod for this?Īlso I would like to find a dead thing mod that REALLY scraps EVERYTHING dead, all of it. I want to know how much of each resorce I have without having to manually scrap every item for contents. I am tried of scrolling through a list of endless items in my workbench. I am looking for a mod that will break down all junk into its base componets as it is added to the workbench. I still can not scrap raiders, gunners, and super mutants, that I know of, there may be more. It lets you scrap a lot of dead things, but not all. Scrap Dead Things, does what the title says. Spring Cleaning lets you scrap most everything within the settlement boundries. Let us know what you think! Leave a comment or submit feedback to the editor.I've been digging through the Nexus site looking for mods to add content to the scrapping process. ![]() We hope these refreshed designs make it easier than ever to stay connected to the latest NIH grant news. You can easily browse by categories like ‘New Resources’ and ‘Tips Before You Submit’ in the main menu. The redesigned site contains the same content you rely on, only now with a modern look and improved browsability. ![]() You will also find a new and improved Extramural Nexus site, your source for news on grants policies, processes, and more. Please add to your safe senders list as you can expect this to be the email address we send from moving forward. Would you like to be notified when we post a new article? You have the option to subscribe to real-time notifications – choose between notifications for every post (including Open Mike), or just the Open Mike blog posts. Any subscriptions you already have for our monthly Extramural Nexus newsletter will continue. We are pleased to announce that we are using a new email subscription service to make it easier for you to receive updates on topics impacting the extramural research community. We have done some spring cleaning! Our Extramural Nexus emails and site have been refreshed to improve your reading and browsing experience. ![]()
0 Comments
4/3/2023 0 Comments Wits and wagers questions pdf![]() ![]() These are the 7 Question Cards that will be used during the game. � The Question Reader should remove 7 Question Cards from the box and place them on the table yellow-side-up. Place the Sand Timer next to the Question Reader. Choose one player to be the Question Reader. Place the Poker Chips next to the Banker. � Write your name (or a witty team name) on your Answer Card. Give each player a paper napkin or tissue to erase their Answer Card in between questions. ����� � Each player (or team) starts with 1 Dry Erase Pen, 1 Answer Card, and 2 cardboard Betting Chips of the same color as their Answer Card. The Host may also participate in the game if they wish. The Host should be both the Question Reader and the Banker. Sometimes it is fun to have someone host Wits & Wagers in the style of a TV game show. Under these conditions, wait an extra 10 – 20 seconds before turning over the sand timer. If playing with larger teams, you may require extra time for answering questions and betting. If you have a large group, we recommend dividing into 7 teams. Be prepared for light-hearted banter, a little bravado, and a big dose of cheering! ���������������� Wits & Wagers is a great team game. ![]() We recommend playing at holiday parties, family reunions, or any large gathering of friends. ������������ Wits & Wagers is most fun with groups of 6 or more people. ![]() The player with the most points after 7 questions wins. Think you know it? Bet on your guess! Think you know who the expert is? Bet on them. ���������������������� �������� Not a trivia buff? It doesn’t matter! Each player writes down a guess to the same question and places it face-up on the betting mat. ![]() 4/3/2023 0 Comments Quotes about relax![]() ![]() ![]() “Some of us don’t need a special day to relax but some of us are so busy that we forget that to relax is also an important thing…. “Relaxation Day is simply a reminder for all of us who are running around all their lives that we deserve to relax and today is the day to do so.” On Relaxation Day, it is the right thing to do.” “Amidst the busy life, we forget that our body, mind and soul need to relax, need to untune with the hectic schedule…. “You work really very hard, you make sure that you fulfil every expectations people have from you but today is Relaxation Day and you must forget everything and just relax.” 58 Relax Quotes The music helped me focus, there were no words, but the instruments and the melody were uplifting, yet relaxing. Have a wonderful Relaxation Day my dear.” ![]() “Having 365 days just to work is not fair and therefore we need some days just to rest and do nothing…. May you have a relaxed day at pool with a good book to read and a great drink to enjoy.” The ocean stirs the heart, inspires the imagination and brings eternal joy to the soul. Give me coffee to change the things I can, and the beach to accept the things I can’t. “Wishing you a very Happy Relaxation Day…. Wherever you go, bring your own sunshine. “Sometimes actions are what complicate many situations and therefore, relaxing and doing nothing sometimes is the right thing to do…. With newest and coolest Happy Relaxation Day messages to share, wish your near and dear ones on Facebook, WhatsApp. While you relax, don’t forget to wish your family and friends with funny relaxing quotes and Relaxation Day greetings to remind them that how important it is to relax. We all get tired running around in life and this day is all about taking a break and getting some relaxation. August 15 th is a very special day as it is Relaxation Day. ![]() 4/3/2023 0 Comments Az screen recorder mac![]() ![]() One of the most important advantages iTop Screen Recorder is that it supports exporting high-quality creations at all times. ITop Screen Recorder is completely free for all users to satisfy the demands to record screen on Windows 10, 11 8, 7. Here are 5 features which make it outstanding. Furthermore, it also supports flexible selection in the recording zone, taking screenshots, multiple output formats, and no lagging in the high definition recording process. ITop Screen Recorder allows you to record audio to express verbally as assistance for a video tutorial and it enables webcam recording. It gives full compatibility with all Windows PC from the latest Windows 11, Windows 10 to Windows 8/7 to screen record in full HD with no effort. Undoubtedly, iTop Screen Recorder is the outstanding one among so many 1080p screen recorders for PC. You just need to record your screen on computer to send it to your colleagues with the help of a HD screen recorder which can make the process of sharing information simple and convenient. No misunderstanding on conveying operational requirements verbally or in writing. No time wasted on waiting for someone to do a demonstration face to face. ![]() #1 HD 1080p Screen Recorder for PC – Windows 11/10/8/7Ī good free screen recorder makes your work easier and it is possible to improve the cooperation efficiency between you and your colleagues. This index will be generated automatically when displayed on the front end.Then you don’t have to waste time trying different screen recorders only for picking out a suitable one. So for your convenience, we sort out 4 best 1080p screen recorders free for PC, Mac, iOS, and Android. However, a rare part of screen recorders supports recording 1080p videos. Since screen-recording technique has come a long way in recent years, and now a great many impressive tools available spring like mushrooms out there. Because, a professional HD screen recorder can help you easily catch all key points, especially for gameplay and movie recording. You can make it if getting a 1080p screen recorder. When it comes to screen recording, most people prefer to capture screen in 1080p HD for sharing a high-quality video with others locally or online. 1080p, also known as Full HD that delivers crisp images, is now the mainstream resolution for movies/TV shows, online videos, games, broadcasts and supported by various devices from computer to mobiles. ![]() ![]() ![]() Named "The Quake" after a vote, the stadium was nicknamed the "Epicenter". Construction started on November 14, 1991. Selling the rights to the name the San Bernardino Spirit to a different franchise, the main staff of Stickney's team moved outside the construction zone where the ballpark would be built. In the early 1990s, Stickney was informed by the city of Rancho Cucamonga that they would be breaking ground on a new stadium. was among the players that came through Fiscalini Field on their way to the big leagues. After spending time in Ventura, California under new ownerships (a group of investors including Roy Englebrecht, actor Mark Harmon, and former Quakes' majority owner Hank Stickney), the team moved to San Bernardino and in 1987 and became the San Bernardino Spirit. She deactivated the team for a year, selling to a group including Ken McMullen. While in Lodi the team won several California League Championships, including 1973, 19.Īfter 1984, the Chicago Cubs pulled out of Lodi, and the franchise's owner Michelle Sprague couldn't find a major league affiliate. The franchise since in 1966 has been affiliated with several major league teams, notably the Los Angeles Dodgers in the late 1970s and the Chicago Cubs in the early 1980s. Several times in its early history, the team was sold from one group of collaborating town residents to another. Until 1984, the team played at Lawrence Park (now Tony Zupo Field) for home games. A team of investors from the city had pooled together $2,500 to start the franchise a few years before, and their first name was the Lodi Crushers. The Quakes franchise has been in existence since 1966 when it played in Lodi, California. Rc spotlight rancho cucamonga quakes professional baseball team.Yusniel diaz of the rancho cucamonga quakes dodgers.In the 2015 season, the Quakes won their second Cal League Championship in franchise history, sweeping the San Jose Giants for their first crown since 1994. After changing their name from the Spirit to the Quakes in 1993 and moving to Rancho Cucamonga, the team plays its home games at LoanMart Field, where the team has broken a number of seasonal attendance records for their league. ![]() The team then went through several new names and ownership changes. ![]() The franchise was founded in Lodi, California in 1966, with its home field as the Tony Zupo Field. They are a Class A – Advanced team in the California League and a farm team of the Los Angeles Dodgers, their third major league affiliate as the Rancho Cucamonga Quakes. The Rancho Cucamonga Quakes are a minor league baseball team in Rancho Cucamonga, California, USA. ![]() 4/3/2023 0 Comments Bandit camp rust gambling![]() If that’s the case then you are at the right place. In-Game Rust Gambling – Bandit Camp Roulette Wheel Here we will be discussing everything you need to know about where to gamble in Rust. If you are looking for ways to gamble in Rust, one of the most common ways you can do that is using the Roulette wheel located in the Bandit Camp area inside Rust or the Bandit Town. To use this roulette wheel, all you have to do is head over to the Bandit Town location and then enter the building where the wheel is located. Once inside the building and in front of the Roulette wheel, you can use your scraps to bet on certain numbered and colored sections on the roulette wheel. ![]() Once you select a certain number on the wheel and the number of scraps that you want to bet, you will spin the wheel, and if it lands on the number that you selected, you will win. The number of scraps that you win will depend on the number that you selected. To find the building in Rust that has the roulette wheel, you will have to go to Bandit Town or the Bandit Camp. To do that, enter a game of Rust and open the map. Once you are looking at the map, try to find the location that has tons of vending machine icons. These icons will have a circular shape and a green color. Inside these circles, there will be an image of a shopping cart.Īnother thing that you would want to know about the Bandit Camp is that no asphalt or main roads lead towards it. ![]() There are only two dirt roads that lead to Bandit Town.Īfter you have located the Bandit Town, all you have to do is walk, run, drive, or fly your way towards it. One thing that you should be careful of while entering Bandit Town is that it is a safe zone, and no weapons are allowed in it. So, don’t go running around with a weapon in your hand all willy-nilly. If you do that or if you shoot your weapon within the area, the NCPs will start shooting at you. If the roulette wheel is not your cup of tea, and you are looking for some other ways for Rust gambling within the game, then you should try opening some Rust Cases. ![]() Instead of betting scraps on a number on a roulette wheel, with Rust cases, you buy in-game cases for real cash and then open them to get a random in-game item out of them. A lot of people prefer this type of gambling because they get to enjoy some guaranteed in-game items instead of potentially losing all their scraps. Opening Rust cases within the game and using some of your scraps to spin an in-game roulette wheel may sound fun, but if you really want to level up your gambling game and want to have a true Rust gambling experience, you should try out online Rust gambling platforms. There are a lot of online Rust gambling platforms out there that allow users to enjoy some gambling games. The best part is that you can use your Rust in-game items to take part in all the gambling activities that these platforms have to offer. Some platforms even offer virtual sportsbooks for placing bets on esports or sports matches. ![]() ![]() ![]() The functions are the first seven labeled black keys on the keyboard. Press the key of the function you wish to change. Press the Advanced button to enter Edit Mode. Just sharing my knowledge on the Keystation Pro 88 controller. Tech tip, updating drivers manually requires some computer skills and patience. Obviously can't do, krell, page 1 or windows 8. M audio keystation pro 88 driver - it also works great for controlling rack modules if you want to use this on the go. Windows 8, firmware and by popular brands. You can also take advantage of miscellaneous options such as Background archiving, turn PC off when done, compression estimation. You can test, lock and repair/recover physically damaged archives or volumes allowing to reconstruct missing parts of multivolume archives. Pluses: There are several versions of RAR, for a number of operating environments: Windows 32 bit and 64 bit, Linux, FreeBSD, DOS, OS/2, MacOS X. Winrar has a very friendly user interface, so that the menus are customizable and offer access to important archive commands like extract, test, comment, protect, and lock, but also other important tools such as scan, convert, or benchmark and hardware test. You can create compression profiles in order to optimize your activity. ![]() Winrar has also an inbuilt viewer for viewing the content of text files within archives. You can use a lot of service functions, such as encryption, archive comments, error logging, etc. Using Winrar you can create multivolume archives, self-extracting archives (also multivolume) using the default or optional SFX modules. It doesn't only open rar files, it can also handle non RAR archives (7-Zip, ACE, ARJ, BZ2, CAB, GZ, ISO, JAR, LZH, TAR, UUE, Z, GZip) management, solid archiving which can raise compression ratio by 10% - 50% over more common methods, particularly when packing a large number of small, similar files. Winrar features wizards for beginners and command line interface for advanced users. You can now handle archives directly from Windows Explorer due to the shell integration including drag-and-drop facility and cascaded context menus. It supports RAR and ZIP 2.0 archives, special algorithms optimized for text, audio, graphics, 32-bit and 64-bit Intel executables compression. Winrar archiver is a powerful tool which allows you to create, manage, and control archive files. 2 - Real Rock RiddimĬOVERS: Official Jah Life Time - Works For The Future Pt. 2 - Real Rock Riddim - 1987 (#dreamsound973)Ġ1-Chicken Chest & Little Wayne - Let Off Sup'mĪLBUM: Jah Life Time - Works For The Future Pt. PRODUCERS PLEASE EMAIL ME IF YOU WANT ME TO DELETE FREE LINKS. Please do not bug us with these sort of requests.Real Rock Return, Real Rock Riddim - 2005 (#dreamsound973)Ġ4-Turbulence - Don't Trust A Soul (Don't Trust Dem)Ġ9-Hawkeye - Thiefing Bwoy (Teefing Bwoy)ġ8-Aiesha Ice (Aishea Ice) - You Make Me Feelġ9-Conrad Crystal & Sugar Roy - Gwaan So ManĢ5-Bobby Crystal - Why You Diss Me (Unlisted)ĪLBUM: Real Rock Return, Real Rock RiddimĬOVERS: Official Real Rock Return, Real Rock Riddim CoverįOR PROMOTIONAL PURPOSES ONLY. So, how can I donate?Ĭlick here to learn more about donating. You must donate to be able to download from our server. We are allocating all funds to the download server for donors since we pay out of pocket to keep everything running. ![]() How are download links prevented from expiring?Īll games are available to be voted on for a re-upload 30 days after they were last uploaded to guard against dead links. This is to deter bots from scraping the site and issuing a DMCA takedown on filehosters. Why do I have to complete captcha to view download links? Every installer is checked for authenticity from GOG.com and integrity before uploading. OMG! My antivirus software is reporting I downloaded malware! What gives? No, this would cost even more time and money. Please use JDownloader 2 to download game files and 7-Zip to extract them. What is the easiest way to download or extract files? Simple! To upload and share games from GOG.com. Frequently Asked Questions What is the purpose of this site? ![]() 4/3/2023 0 Comments In libving colol![]() ![]() The stage was filled the In Living Color cast dancing around as the rappers take turns bouncing from each side of the stage. Gang Starr and Nice & Smooth lifted the energy levels on the In Living Color set to higher heights as they performed “Dwyck,” with DJ Premier laying down his scratches. ![]() On In Living Color, she delivered a rousing performance of her early ’90s, Naughty by Nature-produced hit “Latifah’s Had It Up 2 Here,” where she reminds her detractors that “Queen L-A-T-I-F-A-H in command.” ![]() Queen Latifah solidified her spot as both a gifted MC and actress in the ’90s. Queen Latifah – “Latifah’s Had It Up 2 Here” If there’s a hip-hop song that can unite the masses, it’s Naughty by Nature’s “Hip Hop Hooray.” The group brought their classic to In Living Color in 1993 and turned the show into an afterparty with support from the crowd as they waved their hands to the infectious chorus. In Living Color wasn’t afraid to poke fun at pop culture, and for “White, White, Baby,” then-unknown Jim Carrey took on the role of Vanilla Ice to parody the rapper’s megahit “Ice, Ice, Baby.” The parody called out Ice for appropriating hip-hop culture with lines like, “I’m White, and I’m capitalizing on trend that’s currently rising” and “I’m living large and my bank is stupid/ ‘Cause I just listen to real rap and dupe it.” Jim Carrey as Vanilla Ice – “White, White Baby” The performance saw cameos from Flavor Flav and Tupac. Heavy D’s strong lyrical skills permeated the studio space at In Living Color as he rapped over the classic boom-bap beat and showcased a more hardcore persona than what fans were accustomed to. Heavy D & The Boyz – “You Can’t See What I Can See” Kris Kross needed no backup dancers, but with the indelible lyrics and lively beat, it was hard for the audience and the show’s cast to remain still. In the ’90s, the duo made their mark on hip-hop with the bouncy “Jump” when they were just pre-teens. We have Kris Kross to thank for backward clothing. The crowd’s energy levels rose as soon as Flavor Flav emerged onstage, clad in his signature clock and bold fashion style. ![]() “The boldness in their lyrics, the level of consciousness that they have brought to their lyrics has totally redefined the level of excellence in rap,” Keenen Ivory Wayans said before introducing the group and Ice Cube to perform the anthemic hit on the show. Hip-hop has long been a form of raw expression and reflective of the African-American experience, and Public Enemy’s standout cut “Fight the Power” gave hip-hop one of the genre’s most iconic songs to date. Dre and Snoop Dogg came one of his greatest songs “Real Muthaphukkin G’s.” Despite being broadcast on a national network, In Living Color continued to push the envelope by opening their stage to hip-hop acts like Eazy-E, who performed his dis record on the show in 1994. As she sauntered onto the In Living Color stage, Blige belted out the emotive tune in her signature, soul-drenched croon with her backup dancers - and the show’s cast - bobbing along to the upbeat, drum-laden beat.Īt the climax of Eazy-E’s rivalry with Dr. Blige has been dubbed the Queen of Hip-Hop Soul and proved why she deserved that title with her performance of “Reminisce” from her debut album What’s the 411. Since bounding onto the music scene in the ’90s, Mary J. Bruno Mars & Cardi B's 'Finesse' Remix Takes Memes Back to the '90sĪfter Bruno Mars paid homage to the iconic ’90s show in his “Finesse” remix video with Cardi B, Billboard takes a look back at the best musical performances on In Living Color. ![]() ![]() ![]() ![]() Note that the Enlightened represent a new branch of their cult that is friendlier with players. When you do, you’ll be able to loot them for a chance to earn rare item plans. Stop the Cult from spreading their influence by taking down any High Priests you meet. While the Mothman Equinox event is live, you’ll also encounter hostile Cultist High Priests throughout Appalachia who can bend the will of nearby creatures to do their bidding. As well, if you’re the curious type, you may find that poking around Point Pleasant during this Seasonal Event may “enlighten” you to the mysterious origins behind our newest Mothman fanatics. However, this will be no easy task, as you’ll also need to fend off rival Mothman Cultist groups who seek to stop you. Every hour during this Seasonal Event, you can venture to Point Pleasant to aid the Enlightened in completing this dark ceremony. There, they intend to perform a ritual that will summon the Wise Mothman during the peak of his power. The planets are aligning, and a group of the Wise Mothman’s most devoted followers, known as the Enlightened, have traveled from afar to reach Point Pleasant. ![]() After that Bethesda will probably bring it back once or twice a year and it will then run just one week. This year, it will start on December 8 and run for two weeks till December 21, 2021. The Mothman Equinox is a new Seasonal Event coming with the Night of the Moth update. ![]() ![]() ![]() ![]() The interaction between protomers within the dimer is stabilized by a large number of hydrogen bonds 13.Ībout a decade ago, two low-resolution (23 Å and 30 Å) EM structures of sNS1 were determined: a cryoEM structure reconstructed from images acquired by using a negative-stain room temperature EM structure (Supplementary Fig. 1b) 14 and the other, a 120 kV LaB 6-equipped electron microscope (Philip CM12 TEM) 15. One side of the β-ladder faces the hydrophobic β-roll, while the other side is decorated with its highly charged spaghetti loops. The β-ladder domains from the two iNS1 protomers line up with each other to form a long ladder-like pattern. (3) the β-ladder domain (amino acids 182–352), consists of a continuous arrangement of 10 β-strands. The wing domain is the most flexible domain as it differs between different flavivirus NS1 crystal structures 12. (2) Following the β-roll domain is the wing domain (amino acids 31–181). This domain is generally hydrophobic and is thought to interact with cellular membranes. 1a): (1) the N-terminus contains the β-roll domain (amino acids 1–30) that interacts with the same domain from the other protomer within the dimer to form a roll-like structure (named β-roll). Each protomer of the iNS1 contains three domains (Supplementary Fig. There are also crystal structures of the dimeric form of NS1 protein from other flaviviruses 12 and they are largely similar to that of the DENV iNS1. There is a high-resolution crystal structure of full length dimeric dengue iNS1 11 produced by baculovirus expression and subsequent extraction from cellular membrane compartments. Some NS1 is transported to the cell membrane 10, while others are secreted outside the cell, becoming the sNS1. It forms dimers in the ER and then is glycosylated in the trans-Golgi network. INS1 (45 kDa) is first made in the endoplasmic reticulum (ER) as a monomer. sNS1 is therefore an important viral protein both for viral infection (mammalian cells and mosquitoes) and pathogenesis, and it is important to understand the structure of the sNS1 protein. sNS1 was also found to enhance viral infection in mosquitoes by downregulating mosquito midgut immune genes 9. NS1-immune polyclonal serum and anti-NS1 monoclonal antibodies (MAbs) can protect mice against lethal DENV2 challenge 4. Injection of sNS1 alone also causes vascular leakage in mice 4. ![]() Mice injected with sNS1 along with a sublethal dose of DENV were observed to succumb to infection. sNS1 when bound directly to endothelial cells causes barrier dysfunction of the cell monolayer as demonstrated in an in vitro trans-endothelial electrical resistance (TEER) assay 4, 8. sNS1 likely causes vascular leakage symptoms in DHF/DSS via two pathways-indirectly, by stimulating the innate immune response through activation of complement and Toll-like receptors 7, and directly, by binding to endothelial cells causing endothelial hyperpermeability. The extracellular secreted NS1 (sNS1), exists in higher oligomeric forms. ![]() The intracellular NS1 (iNS1), exists as a membrane associated dimeric form and is a part of the viral replication complex. It is a multifunctional protein which exists in different oligomeric forms intracellularly and extracellularly 6, and they play distinctly different roles. NS1 is secreted alongside dengue virus particles during an infection. It has been shown to play an important role in causing the vascular leakage symptoms in DHF/DSS 4, 5. Recently, dengue non-structural protein 1 (NS1) has been investigated as an alternative protein candidate for vaccine development. It has been proven to be difficult to develop an effective vaccine using whole dengue virus or its surface E protein, as the vaccine would need to stimulate equally strong immune responses simultaneously against all four dengue serotypes or else it can lead to a possibility of antibody-dependent enhancement (ADE) of infection 3. Dengvaxia, which is currently the only licensed dengue vaccine, has an overall efficacy of only 45%, and there is a possibility of priming the previously immune naïve children to develop severe disease in subsequent natural infection after vaccination 2. Dengue virus causes disease that ranges from mild dengue fever to the severe dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) 1. It belongs to the family Flaviviridae, which also includes significant human pathogens, such as West Nile virus (WNV), yellow fever virus (YF) and Zika virus (ZIKV). Dengue is a positive sense single-stranded RNA enveloped virus. ![]() |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |